Abstract
A one-year clinical study was carried out on 181 school children 6 to 11 years old to compare the caries-preventive effect of three commonly used topical fluoride agents: an acid phosphate-fluoride solution (2% NaF, 0.15MH3PO4, pH 3.6), an 8 percent aqueous stannous fluoride solution, and a 2 percent aqueous sodium fluoride solution.Four groups -including the control group- were formed, each group representing as nearly as possible an equal cross section of the entire body of subjects.The most careful procedure of topical application with a tray was used; applications were performed once yearly except in one group. This group was received topical application of a 2 percent aqueous sodium fluoride solution four times in two weeks according to the method of Knutson.Considerable protection was afforded by all three of these agents, and especially by the acid phosphate-fluoride solution.
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