Comparison of the impact of rivaroxaban and low molecular weight heparin on hidden blood loss after unilateral first half artificial hip replacement surgery

Abstract

Objective To investigate the impact of rivaroxaban and low molecular weight heparin on hidden blood loss after unilateral first half artificial hip replacement surgery. Methods According to the digital table, a total of 80 cases because of femoral neck fractures in elderly patients with unilateral arthroplasty artificial hip and a half after surgery were randomly divided into the rivaroxaban group and low molecular weight heparin(LMWH)group,40 cases in each group. In both groups,respectively, after 12 h begin daily oral rivaroxaban 10 mg and subcutaneous low molecular weight heparin 5 000 u,compared the two groups around the actual amount of perioperative blood loss, blood loss was dominant, recessive blood loss and hidden blood loss accounts, the actual percentage of total blood loss, and recorded 35d bleeding events. Results The total amount of blood loss, dominant blood loss, hidden blood loss and the hidden blood loss accounted for the actual percentage of the total amount of blood loss of the rivaroxaban group were(671.00±55.61)mL,(313.88±14.53) mL,(350.00±29.41)mL,(52.00±5.22)%,respectively,which of the the LMWH group were(662.00±30.19)mL,(288.87±15.33)mL,(372.00±35.10)mL,(56.00±6.71)%,there were no significant differences between the two groups(t= 0.93,0.93,0.83,1.03,all P>0.05). Conclusion For patients first underwent unilateral hip replacement surgery artificial half, perioperative using rivaroxaban or LMWH has no significantly differences in hidden risk of bleeding and bleeding event rate. Key words: Arthroplasty, Replacement, Hip; Postoperative Hemorrhage; Rivaroxaban; Low Molecular Weight Heparin