Abstract

Background The introduction on the market of genetically modified (GM) foods has raised the question of the assessment of the potential allergenicity of the newly expressed protein (s) and of the whole GM food. We aimed at comparing the immune responses induced in mice after experimental sensitization with the insect resistant GM maize MON810 expressing the Cry1Ab protein vs its conventional counterpart.

Highlights

  • The introduction on the market of genetically modified (GM) foods has raised the question of the assessment of the potential allergenicity of the newly expressed protein (s) and of the whole GM food

  • Comparison of the immune response induced in mice experimentally sensitized with genetically modified MON810 maize vs its conventional counterpart

  • Humoral and cellular immune responses against endogenous maize proteins were quantitatively equivalent in mice treated with MON810 vs its non GM counterpart

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Summary

Background

The introduction on the market of genetically modified (GM) foods has raised the question of the assessment of the potential allergenicity of the newly expressed protein (s) and of the whole GM food. We aimed at comparing the immune responses induced in mice after experimental sensitization with the insect resistant GM maize MON810 expressing the Cry1Ab protein vs its conventional counterpart

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