Comparison of the effects of Baimai ointment and baclofen in stroke patients with spasticity

Abstract

Objective To compare the effects of Baimai ointment and baclofen in stroke patients with spasticity. Methods 84 cases accompanied by limb spasticity in stroke patients by digital table were randomly divided into Baimai ointment group and baclofen group, 42 cases in each group.The Baimai ointment group were treated with Baimai ointment on the spastic limbs, the baclofen group received oral baclofen tablets 30-75mg/days for 2 weeks, 4 weeks, 8 weeks.The curative effects of the two groups were compared before and after treatment. Results Before and after treatment in the two groups, the levels of spasticity, pain and activities of daily living (ADL) differences were statistically significant and Baimai ointment in the treatment of spasm.After 4 weeks and 8 weeks, the Ashworth score of the Baimai ointment group were (1.59±0.46)points, (0.89±0.56)points, and those of baclofen group were (1.75±0.64)points, (1.45±0.48)points, the differences were statistically significant(t values were 2.916, 3.367, all P<0.05). After 2 weeks, 4 weeks and 8 weeks, the VAS score of the Baimai ointment group were (2.72±0.54)points, (2.02±0.24)points, (1.24±0.12)points, and baclofen group were (3.56±0.44)points, (3.15±0.48)points, (2.58±0.26)points, the differences were statistically significant(t values were 2.975, 3.359, 5.416, all P<0.05), activities of daily living (ADL) was higher than that of the baclofen group.After 8 weeks, the MBI score of the Baimai ointment group was (64.46±10.78)points, and baclofen group was (50.74±9.18)points, the difference was statistically significant between the two groups (t values was 3.562, P<0.05). Conclusion Baimai ointment has the better antispasmodic effect than baclofen in patients with stroke. Key words: Baimai ointment; Baclofen; Stroke; Spasticity