Abstract
Background and AimsRecent introduction of the Cosmed K4b2 portable metabolic analyzer allows measurement of oxygen consumption outside of a laboratory setting in more typical clinical or household environments and thus may be used to obtain information on the metabolic costs of specific daily life activities. The purpose of this study was to assess the accuracy of the Cosmed K4b2 portable metabolic analyzer against a traditional, stationary gas exchange system (the Medgraphics D-Series) during steady-state, submaximal walking exercise.MethodsNineteen men and women (9 women, 10 men) with an average age of 39.8 years (±13.8) completed two 400 meter walk tests using the two systems at a constant, self-selected pace on a treadmill. Average oxygen consumption (VO2) and carbon dioxide production (VCO2) from each walk were compared.ResultsIntraclass Correlation Coefficient (ICC) and Pearson correlation coefficients between the two systems for weight indexed VO2 (ml/kg/min), total VO2 (ml/min), and VCO2 (ml/min) ranged from 0.93 to 0.97. Comparison of the average values obtained using the Cosmed K4b2 and Medgraphics systems using paired t-tests indicate no significant difference for VO2 (ml/kg/min) overall (p = 0.25), or when stratified by sex (p = 0.21 women, p = 0.69 men). The mean difference between analyzers was – 0.296 ml/kg/min (±0.26). Results were not significantly different for VO2 (ml/min) or VCO2 (ml/min) within the study population (p = 0.16 and p = 0.08, respectively), or when stratified by sex (VO2: p = 0.51 women, p = 0.16 men; VCO2: p = .11 women, p = 0.53 men).ConclusionThe Cosmed K4b2 portable metabolic analyzer provides measures of VO2 and VCO2 during steady-state, submaximal exercise similar to a traditional, stationary gas exchange system.
Highlights
Measurement of the oxygen and carbon dioxide content of expired air during exercise is vital to the assessment of cardiovascular function and energy expenditure prediction
Our laboratory intends to use the Cosmed K4b2 during submaximal testing of over-the-ground walking, this study aims to assess the accuracy of measuring VO2 and VCO2 by the Cosmed K4b2 system using a Medgraphics D-series gas exchange system (Medgraphics, Medical Graphics Corporation, St Paul, MN), a widely used breath-by-breath analyzer, as the reference standard during a steady-state walking test [12,13]
The exercise modality, duration and intensity utilized in this testing protocol were selected to simulate the Long Distance Corridor Walk (LDCW) test which has been validated as a method of assessment of physical function in the elderly [4]
Summary
Measurement of the oxygen and carbon dioxide content of expired air during exercise is vital to the assessment of cardiovascular function and energy expenditure prediction. In individuals with substantially reduced VO2 Max, because of disease or disability, the oxygen consumption required to perform activities of daily living may represent a larger percentage of VO2 Max, and may theoretically be a limiting factor for independence. Recent introduction of the Cosmed K4b2 portable metabolic analyzer (Cosmed K4b2, Cosmed, Rome, Italy) allows measurement of VO2 outside of a laboratory setting in more typical clinical or household environments and may be used to obtain information on the metabolic costs of specific daily life activities. Recent introduction of the Cosmed K4b2 portable metabolic analyzer allows measurement of oxygen consumption outside of a laboratory setting in more typical clinical or household environments and may be used to obtain information on the metabolic costs of specific daily life activities. The purpose of this study was to assess the accuracy of the Cosmed K4b2 portable metabolic analyzer against a traditional, stationary gas exchange system (the Medgraphics D-Series) during steady-state, submaximal walking exercise
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