Abstract
1345 This study compared the fat (%BF) and fat-free body (FFB) composition of spinal cord injured (SCI) adults to values for able-bodied (AB) women and men. Subjects were 91 SCI men (n=66) and women (n=25), 18-73 yr. Dual energy x-ray absorptiometry (DXA; Hologics QDR-1000, software 6.1) was used to assess%BF, bone mineral content (BMC), and bone mineral density (BMD). Deuterium oxide(D20) dilution and mass spectrometry were used to assess total body water(TBW). The relative proportions and corresponding densities of TBW, total body mineral (TBM), and total body protein (TBP) were used to estimate FFB density. While the average BMD and TBM/FFB of SCI women (1.06 g/cm2 & 7.0% FFB, respectively) were similar to those of age-matched norms for AB women (1.05 g/cm2 & 7.3% FFB), the average BMD and TBM/FFB of SCI men (1.07 g/cm2& 5.5% FFB) were significantly (p<.05) less than those of AB men (1.13 g/cm2 & 6.8% FFB). The average TBW/FFB for SCI men (66.3% FFB) and women(69.4% FFB) was significantly (p<.05) less than reference values of AB adults (72-73% FFB). Thus, the average TBP/FFB for SCI women (23.6% FFB) and men (28.2% FFB) was significantly (p<.05) greater than that of AB men(19.4% FFB) and women (19.7% FFB). The overall FFB density for SCI women and men (1.114 & 1.116 g/cc, respectively) was larger than the assumed value(1.100 g/cc) for the reference body. Also, the average%BF of SCI women (34.2%) and men (26.7%) was high, placing many SCI individuals at-risk for diseases associated with obesity. These data demonstrate that the FFB composition of SCI adults differs from that of AB persons; thus, FFB composition must be taken into consideration when developing and validating practical methods and prediction equations to assess body composition of this population in clinical settings.
Published Version
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