Comparison of T‐recoil and Wilzbach labeling of methylamine (preparation of methylamine‐CH2T)

Abstract

AbstractRecoil labeling of methylamine via the 6Li(n,α) T‐reaction, using solutions of LiBr in liquid anhydrous methylamine, leads to a 10% radiochemical yield of methylamine‐CH2T. The yield is independent of the accompanying radiation dose within a wide range, thus allowing high‐dose pile irradiation. Specific activities up to 100 μC/mM can easily be obtained. For comparison Wilzbach labeling of gaseous methylamine has also been studied. Here, in contrast, poor tritium incorporation is observed, the L‐value for methylamine‐CH2T being 2.3 × 10−2.