Abstract
Background: The aim of this study is to evaluate the preoperative, intraoperative and postoperative differences in patients who underwent splenectomy for benign and malignant diseases.
 Materials and Methods: Adult patients (18 years and older) who underwent splenectomy in a tertiary health center between January 2015 and January 2021 were searched retrospectively. The patients were divided into two main indication groups: patients who underwent splenectomy for benign diseases (n=35) and patients who underwent splenectomy during malignancy surgery (n=45). In addition, benign indications were also divided into three subgroups. Clinicopathological variables obtained from the patients' medical records were compared between both main groups and subgroups.
 Results: The mean age of 80 patients who met the study criteria was 53.47±18.28 (18-86), and 44 patients (55%) were female. The mean age of the patients, laparoscopic surgery rate, elective surgery rate, postoperative complication rate, need for erythrocyte suspension and fresh frozen plasma, length of hospital stay and length of stay in the intensive care unit were higher in the malignancy group. In addition, splenectomy cases due to malignancy were proportionally higher in recent years. Another important result of the study was that traumatic splenectomies require longer hospitalization, and the management of these patients' clinics is more difficult than other benign splenectomy causes.
 Conclusion: Among all splenectomy cases, malignant splenectomy cases and benign splenectomy cases who underwent traumatic splenectomy are difficult to manage because of longer hospital stay, more need for blood products, and high morbidity rates.
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