Comparison of Pap Smear and Colposcopy in Detection of Premalignant Lesions of Cervix

Abstract

ABSTRACTObjectiveComparison of papanicolaou (pap) smear and colposcopy in detection of premalignant lesions of cervix.Materials and methodsA prospective clinical study was conducted in a tertiary care referral institute in 100 symptomatic, sexually active women of 20 to 60 years. All women were subjected to pap smear, colposcopy and cervical biopsy to confirm the diagnosis.ResultsOut of 49 positive on pap smear, 24 were true positives and 25 were false positives. Out of 51 negative pap smear findings, 45 were true negatives and 6 were false negatives. Thirty percent women had positive histopathology and colposcopic findings. Forty percent women had normal colposcopy with negative histopathology whereas 30% had positive colposcopic findings but negative histopathology. Nineteen percent of women with negative cytology were positive on colposcopy and histopathology.ConclusionPap smear had a sensitivity of 80% and a specificity of 64.29% with positive predictive value of 48.98% and negative predictive value of 88.24% while sensitivity and specificity of colposcopy were 100 and 57.14% respectively and positive predictive value and negative predictive value of colposcopy were found to be 50 and 100% respectively.How to cite this articleKohli B, Arya SB, Goel JK, Sinha M, Kar J, Tapasvi I. Comparison of Pap Smear and Colposcopy in Detection of Premalignant Lesions of Cervix. J South Asian Feder Menopause Soc 2014;2(1):5-8.