Abstract
Background: Menopause is a natural biological phenomenon during which irreversible changes in the hormonal and reproductive functions of the ovaries lead to physical, social, and psychological changes in women. The progressive loss of estrogen and its protective effects predisposes to the development of oxidative stress and related diseases in postmenopausal women which, in turn, can impair their quality of life. Aims and Objectives: This study aims to study and compare the levels of serum malondialdehyde (MDA) and superoxide dismutase (SOD) in premenopausal and postmenopausal females. Materials and Methods: A cross-sectional comparative study was conducted in 100 healthy women, of which 50 were postmenopausal in the age group of 5060 years and 50 were premenopausal in the age group of 3040 years. The data were analyzed using Statistical Package for the Social Sciences version 18. Results: Oxidative stress was increased in postmenopausal women as evidenced by significantly elevated MDA and reduced SOD. Conclusion: Menopause is associated with oxidative stress which predisposes to the development of cardiovascular diseases, vasomotor disturbances, osteoporosis, depression, diabetes, and hypertension. Dietary management, antioxidant supplementation, and moderate physical activity would help them to prevent diseases related to menopause.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: National Journal of Physiology, Pharmacy and Pharmacology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.