Comparison of Oral Agents for Treatment of Pneumocystis carinii Pneumonia

Abstract

Letters1 March 1997Comparison of Oral Agents for Treatment of Pneumocystis carinii PneumoniaSharon Safrin, MD and Dianne Finkelstein, PhDSharon Safrin, MDUniversity of California, San Francisco, San Francisco, CA 94110Harvard University School of Public Health, Boston, MA 02115Search for more papers by this author and Dianne Finkelstein, PhDUniversity of California, San Francisco, San Francisco, CA 94110Harvard University School of Public Health, Boston, MA 02115Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-5-199703010-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Because space constraints made it necessary to select the categories of toxicity to be reported in our article, hyperkalemia was not specifically reported. In response to Dr. Perazella's query, however, we specifically looked at the occurrence of hyperkalemia in patients receiving clindamycin-primaquine, dapsone-trimethoprim, or trimethoprim-sulfamethoxazole in the ACTG (AIDS Clinical Trials Group) 108 trial.Table 1 summarizes all categories of hyperkalemia that occurred in study patients while they were actually receiving assigned therapy. No grade IV toxicities occurred. A single instance of grade III hyperkalemia occurred in a patient receiving dapsone-trimethoprim; this patient had the one case of ... Author, Article, and Disclosure InformationAffiliations: University of California, San Francisco, San Francisco, CA 94110Harvard University School of Public Health, Boston, MA 02115 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySuccessful Conservative Management of Trimethoprim Induced Life-Threatening Hyperkalaemia in a Patient with Pneumocystis jirovecii PneumoniaTrimethoprim-Induced HyperkalaemiaMiscellaneous antibacterial drugsAntiprotozoal drugs 1 March 1997Volume 126, Issue 5Page: 407-408KeywordsAIDSBody weightClinical trialsPneumocystis carinii pneumoniaPotassiumToxicity Issue Published: 1 March 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...