Abstract
Letters15 February 1995Atovaquone for Pneumocystis carinii PneumoniaMichael M. Lederman and Charles van der HorstMichael M. LedermanSearch for more papers by this author and Charles van der HorstSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-4-199502150-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We are concerned that the article by Dohn and colleagues [1] may have overstated the efficacy of oral atovaquone for the treatment of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome (AIDS). The study is described as an equivalency trial, that is, a test of the hypothesis that using oral atovaquone is not worse than using intravenous pentamidine for the treatment of AIDS-associated P. carinii pneumonia. The authors reported that the hypothesis was confirmed; in this small study, treatment failures were not significantly more frequent in the atovaquone group than in the pentamidine group. However, ...REFERENCE1. Dohn MN, Weinberg WG, Torres RA, Follansbee SE, Caldwell PT, Scott JD, et al. Oral atovaquone compared with intravenous pentamidine for Pneumocystis carinii pneumonia in patients with AIDS. Ann Intern Med. 1994; 121:174-80. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAtovaquoneANTIPROTOZOAL AND ANTIHELMINTHIC DRUGSAtovaquone 15 February 1995Volume 122, Issue 4Page: 314-315KeywordsAIDSAtovaquonePneumocystis carinii pneumoniaPneumonia Issue Published: 15 February 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
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