Comparison of ocular wavefront aberrations in subluxated lenses before and after lens extraction with intraocular lens implantation

Abstract

To compare the change in ocular higher-order wavefront aberrations (HOAs), visual acuity, and modulation transfer function (MTF) after lens extraction with intraocular lens (IOL) implantation in patients with subluxated lenses. Iladevi Cataract & IOL Research Centre, Ahmedabad, India. Prospective case series. Eyes with subluxated lenses having lens extraction with IOL implantation were included. Capsular bag fixation with in-the-bag IOL implantation or sutured or sutureless scleral fixation of the IOL was performed. Aberrometry was performed preoperatively and 6months postoperatively. The following were compared: root-mean-square (RMS) value for total ocular HOAs, coma aberration, spherical aberration, MTF, and corrected distance visual acuity (CDVA). Of the 39 eyes with subluxated lenses, 26 eyes had Cionni ring fixation, 9 had sutured scleral fixation, and 4 had intrascleral fixation of the IOL. The mean preoperative and postoperative values, respectively, were as follows: RMS HOAs, 10.5μm±9.5 (SD) and 4.73±4.6μm(P<.001); coma aberration, 2.46±2.4μm and 0.11±0.1μm(P=.03); and spherical aberration, 0.37±0.9μm and 0.02±0.06μm(P=.02). The MTF improved significantly in all eyes (mean 0.05±0.02 preoperatively and 0.32±0.16 postoperatively) (P=.005). The CDVA was statistically significant improved 6months postoperatively. Lens extraction with IOL fixation in eyes with subluxated lenses significantly reduced ocular HOAs and improved the MTF.