Abstract
The chromatographic properties of C 18 bonded reversed-phase thin-layer chromatography plates have been compared with paraffin-coated silica gel thin-layer chromatography plates for the reversed-phase chromatography of a range of organic compounds. These included non-steroidal anti-inflammatory drugs, ecdysteroids, aminophenols, hydroxybenzoic acids and antipyrine. Both types of plate can be used with mobile phases containing up to 100% water, allowing a wide choice of solvent systems. Although differences were found between bonded and coated plates in most applications they are interchangeable following minor adjustments to the mobile phase.
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