Comparison of mechanical properties of human, bovine bone and a new processed bone xenograft

Abstract

The study compared the mechanical properties of human bone, fresh bovine bone and a new highly purified bone xenograft: T650 (Lubboc-Laddec). Destructive, compressive tests were performed to determine Young's modulus and ultimate strength, with a constant deformation rate of 0.025 mm min −1. The stress-strain curves obtained from all the non-human specimens, especially the T650, did not differ significantly from those observed with human bone. Human and fresh bovine samples presented a significantly different Young's modulus. The T650 samples, depending upon their trabecular texture (dense or medium) also differed significantly from each other (132.9 ± 52.3 versus 80.0 ± 37.3 MPa, P < 0.05). Their moduli were similar to those of bovine and human cancellous bone, respectively (117.49 ± 61.53 versus 77.36 ± 54.96, P < 0.05). The ultimate strength of T650 dense (9.6 ± 3.7 MPa) was similar to bovine (8.5 ± 4.2 MPa) and human bone (8.78 ± 5.2 MPa); the T650 medium (5.9 ± 2.8 MPa) was significantly different from the other specimens.