Comparison of manual and semi-automated analysis tools for quantifying left ventricular volumes and mass in Children

Jennifer A Bryant,Mark A Hanson,Charles R Peebles,Sheila Barton,Keith M Godfrey

doi:10.1186/1532-429x-13-s1-p358

Jennifer A Bryant, Mark A Hanson + Show 3 more

Open Access

https://doi.org/10.1186/1532-429x-13-s1-p358

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Abstract

CMR is an accurate and reproducible technique for the analysis of left ventricular volumes in adults but less well validated in children. Various analysis tools and segmentation methods are available but it is not clear which is most appropriate for use in children. Conventional manual segmentation tools require time-consuming contour tracing but allow some compensation for image mis-registration. The semi-automated tool (Argus 4D, Siemens Healthcare) employs a heart model based algorithm with reported significantly reduced analysis times but correction for the image mis-registration more frequently seen in children is more difficult.

Highlights

cardiovascular magnetic resonance (CMR) is an accurate and reproducible technique for the analysis of left ventricular volumes in adults but less well validated in children
To compare manual and semi-automated analysis tools used for the assessment of left ventricular (LV) volumes and mass measured using cardiovascular magnetic resonance (CMR)
The estimated coefficient of variation for stroke volumes (SV) measurements calculated using Osirix was lower than that using Argus 4D (10.6% vs 13.1%)

Summary

Introduction

CMR is an accurate and reproducible technique for the analysis of left ventricular volumes in adults but less well validated in children. Various analysis tools and segmentation methods are available but it is not clear which is most appropriate for use in children. Conventional manual segmentation tools require timeconsuming contour tracing but allow some compensation for image mis-registration. The semi-automated tool (Argus 4D, Siemens Healthcare) employs a heart model based algorithm with reported significantly reduced analysis times but correction for the image misregistration more frequently seen in children is more difficult. Purpose To compare manual and semi-automated analysis tools used for the assessment of left ventricular (LV) volumes and mass measured using cardiovascular magnetic resonance (CMR)

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Results

Conclusions