Abstract
Objective To compare the intraoperative wake-up test performed under different methods of anesthesia in the patients undergoing scoliosis correction. Methods Sixty American Society of Anesthesiologists physical status Ⅰ or Ⅱ patients of both sexes, aged 14-35 yr, undergoing elective scoliosis correction, were divided into dexmedetomidine-based anesthesia group(D group)and sevoflurane-based anesthesia group(S group), with 30 cases in each group.Patients were tracheally intubated after induction of anesthesia.Maintenance of anesthesia was as follows: remifentanil 0.3 μg·kg-1·min-1 was intravenously infused, dexmedetomidine 0.2 μg·kg-1·h-1 was intravenously infused in group D, and group S inhaled low flow sevoflurane 1 L/min with the end-tidal concentration of 0.8%-1.5%.Narcotrend index value was maintained at 30-45.The wake-up time, adverse events, requirement for vasoactive agents and blood loss during wake-up test were recorded.The wake-up quality was evaluated. Results All the patients successfully completed wake-up tests.Compared with group S, the wake-up quality was significantly increased, the incidence of agitation and bucking was decreased during wake-up test, the blood loss was reduced during wake-up test(P 0.05). Conclusion Dexmedetomidine-based anesthesia produces better efficacy for intraoperative wake-up test than sevoflurane-based anesthesia in the patients undergoing scoliosis correction. Key words: Dexmedetomidine; Anesthetics, inhalation; Scoliosis; Wake-up test
Published Version
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