Abstract
Background: Hypertension is the major health problem throughout the world because of its high prevalence and its association with increased risk of cardiovascular diseases. Aim : The aim of present study was to evaluate the hematological changes in primary hypertension in Sangareddy, Andhra pradesh. Materials and Methods: In the present study, a total of 100 patients diagnosed for primary hypertension and 100 normotensive subjects were included. All the participants after taking informed consent were subjected to detailed history and hematological analysis. Students-’t’ test was used to find out the significance of differences. P values less than 0.05 was considered the level of significance. Result: It was observed that the mean values of Hemoglobin, Erythrocyte count, Hematocrit, MCH and MCHC were increased in primary hypertension while, the mean levels of MCV were found to be lower in the hypertensive group when compared to normotensive subjects. Conclusion: Hypertension has impact on hematocrit, hemoglobin, RBC count, WBC count and Platelet count which can be used for early detection of hypertensive prone individuals.
Highlights
Hypertension is the major health problem throughout the world because of its high prevalence and its association with increased risk of cardiovascular diseases[1]
These studies increase knowledge of the pathophysiology of blood pressure control, it is important to differentiate between factors that are altered before the actual blood pressure increase and factors that respond to the blood pressure changes[2]
4.1 Hemoglobin & Erythrocyte count In the present study, the mean levels of Hemoglobin and Erythrocyte count were found to be significantly higher in the hypertensive group
Summary
Hypertension is the major health problem throughout the world because of its high prevalence and its association with increased risk of cardiovascular diseases[1]. A growing number of variables are being identified in population cross-sectional studies or in laboratory studies that are related to mechanisms involved in blood pressure control These studies increase knowledge of the pathophysiology of blood pressure control, it is important to differentiate between factors that are altered before the actual blood pressure increase and factors that respond to the blood pressure changes[2]. Hypertension is a major public health problem in India and in other developing countries This is obvious from several Indian urban and rural studies. Result: It was observed that the mean values of Hemoglobin, Erythrocyte count, Hematocrit, MCH and MCHC were increased in primary hypertension while, the mean levels of MCV were found to be lower in the hypertensive group when compared to normotensive subjects.
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