Comparison Of Fresh Embryo Donation Results In Azoospermic Couples With Embryo Transfer In Tubal Factor Infertility

Abstract

Background and objective: In Iran sperm donation is prohibited for azoospermic infertile couples, so our objective was to compare fresh embryo donation results in azoospermic couples with embryo transfer in tubal factor infertile couples.Material and Methods: A retrospective study was conducted on two hundred twenty five women in a private infertility center. Fresh embryo donation and their comparison group consisted of 158 and 67 patients, respectively. Donors (women with tubal factor infertility),entered the stimulation cycle; simultaneously, endometrium of the recipients (women with azoospermic husband), were prepared by hormonal drugs. After transvaginal, ultrasound guided oocyte retrieval and intracytoplasmic sperm injection ( ICSI); fresh embryo (2days after fertilization) was transferred transcervically to the recipient. In tubal factor infertile group the same procedures were performed as the above with the gametes of the genetic parents. Fertilization and implantation rates, chemical pregnancy, and clinical pregnancy were compared between two groups. Result(s): Fertilization and implantation rate, clinical pregnancy, chemical pregnancy and blighted ovum were not significantly different between two groups. Conclusion(s): We determined that fresh embryo donation has comparable results with embryo transfer in tubal factor infertile couples