Abstract
Knowledge of the Young's modulus distribution of an atherosclerotic artery allows for differentiation between its components. Intravascular elastography generates an artifactual image of this Young's modulus distribution. A finite element model (FEM) can assist in interpreting the elastogram and give its Young's modulus distribution by inverse problem solution. Intravascular ultrasound (IVUS) measurements were performed on a hard phantom with soft eccentric plaque and an atherosclerotic coronary artery. The complex FEM geometry and Young's modulus distribution were defined using a custom-made graphical user interface. Next elastograms were calculated from IVUS data and compared with FEM elastograms. IVUS and FEM elastograms showed excellent agreement in case of the phantom and a similar pattern in case of the artery. Strain values in the FEM elastogram appeared highly sensitive for variations in the Young's modulus but not in the Poisson's ratio.
Published Version
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