Comparison of different devices to measure the intraocular pressure in thyroid-associated orbitopathy.

Abstract

To evaluate the correlation of the intraocular pressure measurements (IOP) with non-contact tonometer Corvis Scheimpflug technology (Corvis ST), Goldmann applanation tonometry (GAT), ocular response analyzer (ORA), and iCARE rebound tonometer in patients with thyroid-associated orbitopathy (TAO) and eye-healthy subjects (control group). Twenty-nine consecutive patients with TAO (79% female) and 30 eye-healthy subjects (60% female) were included in this prospective, age- and sex-matched study. The IOP measurement with Corvis, ORA, GAT, iCARE, and central corneal thickness (CCT) with Corvis was obtained from all study participants. The mean age of the patients was 51 ± 10years in patients with TAO and 56 ± 13years in the control group. The mean IOP measurements with GAT, Corvis, ORA, and iCARE were 15.93 ± 4.42mmHg, 18.10 ± 7.54mmHg, 18.40 ± 7.93mmHg, and 16.61 ± 7.96mmHg in patients with TAO and 14.52 ± 3.02mmHg, 14.48 ± 3.38mmHg, 15.29 ± 4.64mmHg, and 14.13 ± 3.85mmHg in the control group (P = 0.157, P = 0.004, P = 0.017, and P = 0.176 respectively). The mean CCT was 547.5 ± 39.2μm in patients with TAO and 560.8 ± 49.8μm in the control group ( P= 0.261). The data collected shows an agreement between the iCARE and GAT IOP measurements in TAO patients and in eye-healthy patients. However, the mean value of IOP measurements with Corvis and ORA was significantly higher in patients with TAO in comparison with the control group (P = 0.044 and P = 0.029 respectively).