Abstract

BackgroundAnterior cruciate ligament (ACL) revision surgery has been associated with inferior outcome compared with primary ACL reconstruction. However, this has rarely been investigated in a consecutive cohort limited to patients that have undergone both primary and revision ACL reconstruction. This study aimed to assess differences in outcome and concomitant injuries between primary and revision ACL reconstruction in such a cohort, and to identify predictors of the patient-reported outcome after ACL revision.MethodsPatients who had undergone both primary and revision ACL reconstruction were identified in the Swedish National Knee Ligament Registry. Patients aged 13–49 years with hamstring tendon primary ACL reconstruction and data on the Knee Injury and Osteoarthritis Outcome Score (KOOS) on at least one occasion (preoperative or one year postoperatively) at both surgeries were eligible. Concomitant injuries and the KOOS were compared between each patient’s primary and revision ACL reconstruction. Linear regression analyses were performed to determine predictors of the one-year KOOS after ACL revision.ResultsA total of 1014 patients were included. Cartilage injuries increased at ACL revision (p < 0.001), as 23.0% had a cartilage injury at ACL revision that was not present at primary ACL reconstruction. The 1-year KOOS was lower after ACL revision compared with primary ACL reconstruction, with the largest difference in the KOOS sports and recreation (5.2 points, SD 32.2, p = 0.002). A posterolateral corner (PLC) injury at ACL revision was a negative predictor of KOOS, with the largest effect on the sports and recreation subscale (β = − 29.20 [95% CI − 50.71; − 6.69], p = 0.011). The use of allograft for ACL revision was an independent predictor of a poorer KOOS QoL (β = − 12.69 [95% CI − 21.84; − 3.55], p = 0.0066) and KOOS4 (β = − 11.40 [95% CI − 19.24; − 3.57], p = 0.0044).ConclusionPatients undergoing ACL revision reported a 1-year outcome that was slightly inferior to the 1-year outcome after their primary ACL reconstruction. An ACL revision was associated with an increase in cartilage injuries. A PLC injury at ACL revision and the use of allograft for ACL revision predicted a clinically relevant poorer KOOS one year after ACL revision.

Highlights

  • Anterior cruciate ligament (ACL) revision surgery has been associated with inferior outcome compared with primary ACL reconstruction

  • Meniscal injuries decreased at ACL revision (p < 0.001), as the reported meniscal status changed from injured at primary ACL reconstruction to uninjured at ACL revision in 277 patients (27.3%), while 183 patients (18.0%) had their first registered meniscal injury at ACL revision

  • The prevalence of cartilage injuries increased from primary to revision ACL reconstruction (p < 0.001), as 23.0% of the cohort were identified with a cartilage injury at ACL revision that was not present at primary ACL reconstruction

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Summary

Introduction

Anterior cruciate ligament (ACL) revision surgery has been associated with inferior outcome compared with primary ACL reconstruction. This has rarely been investigated in a consecutive cohort limited to patients that have undergone both primary and revision ACL reconstruction. Data from large knee ligament registries have shown that the probability of needing ACL revision surgery within 3 years of the primary ACL reconstruction is generally low, ranging from 2.8 to 3.7% [1]. An ACL revision has been associated with inferior patient- and clinician-reported outcome and a greater likelihood of developing tibiofemoral osteoarthritis compared with a primary ACL reconstruction [3, 4]. The failure rate for ACL revisions is nearly three to four times higher compared with primary ACL reconstructions [4]

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