Abstract
Introduction: This study was done to determine the mean difference and correlation between fasting capillary and venous glucose estimation.
 Methods: This was cross-sectional analytic study done in United Mission Hospital, Palpa, Tansen. Calculated sample size was 92, convenience sampling technique was used. During 5 month of duration in 92 diabetic patients, where fasting capillary and venous glucose were performed consecutively. Confounding was ruled out with matching approach, adjustment tests were also used like X2 Mantel -Haenszel and logistic regression. Reporting guideline of this observational study was done with the help of SROBE guidelines.
 Results: The mean venous blood glucose was 9.52% higher than the Mean capillary glucose. A strong correlation was observed between venous and capillary blood glucose, with Pearson correlation coefficient of 0.94.
 Conclusions: There is a significant difference in the blood glucose results analyzed on a bedside glucometer when the samples are taken from capillary or venous sources. Although good correlation is between venous and capillary derived samples, caution must be exercised in accepting the results as equivalent or using either as substitutes for a laboratory blood glucose result.
Highlights
This study was done to determine the mean difference and correlation between fasting capillary and venous glucose estimation
There have been many concern raised about the accuracy of capillary blood glucose estimation in the face of systemic illness, and it has been suggested that in Correspondence: Dr Bibek Rajbhandari, Department of General Practice and Emergency Medicine, Nepal Police Hospital, Kathmandu, Nepal
This study shows that capillary blood glucose underestimates venous blood glucose in fasting condition which was opposite to the study done by Elizabeth et al in pediatric population
Summary
This study was done to determine the mean difference and correlation between fasting capillary and venous glucose estimation. According to the latest WHO data published in April 2011 Diabetes Mellitus deaths in Nepal reached 3224, 2.17% of total death and the figure is expected to increase to 366 million in 2030 worldwide.[1,2] The Nepal Diabetic Association reported that the diabetes affects approximately 15% of the people over 20 years and 19% of the people over 40 years of the age in the urban areas of Nepal.[3] such patients, venous sampling may be more accurate.[4] Many studies have concluded that glucometers should not be used for diagnosis, only for self-monitoring.[5] In the present study, ascorbic acid, uric acid, a maltose, aspirin, icodextrin and acetaminophen cause around 11% difference in glucose levels.[6]. The objective of this study is to compare capillary and venous blood glucose in diabetic population. There have been many concern raised about the accuracy of capillary blood glucose estimation in the face of systemic illness, and it has been suggested that in Correspondence: METHODS
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