Abstract
Meningiomas are the most common intracranial tumor in dogs and cats, and their surgical resection is often performed because they are present on the brain surface. Typical meningiomas show comparatively characteristic magnetic resonance imaging findings that lead to clinical diagnosis; however, it is necessary to capture not only macroscopic changes but also microstructural changes to devise a strategy for surgical resection and/or quality of removal. To visualize such microstructural changes, diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) have been used in human medicine. The aim of this retrospective study was to investigate the different characteristics of the apparent diffusion coefficient (ADC) from DWI and fractional anisotropy (FA) from DTI of meningioma between dogs and cats. Statistical analyses were performed to compare ADC and FA values between the intratumoral or peritumoral regions and normal-appearing white matter (NAWM) among 13 dogs (13 lesions, but 12 each in ADC and FA analysis) and six cats (seven lesions). The NAWM of cats had a significantly lower ADC and higher FA compared to dogs. Therefore, for a comparison between dogs and cats, we used ADC and FA ratios that were calculated by dividing the subject (intra- or peritumoral) ADC and FA values by those of NAWM on the contralateral side. Regarding the intratumoral region, feline meningiomas showed a significantly lower ADC ratio and higher FA ratio than canine meningiomas. This study suggested that ADC and FA may be able to distinguish a meningioma that is solid and easy to detach, like as typical feline meningiomas.
Highlights
Meningiomas are the most common intracranial tumor in dogs and cats
There was a significant difference in the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values of dogs and cats in the normal-appearing white matter (NAWM) on the contralateral side to the lesion
In agreement with our hypothesis, we found that feline meningiomas had lower ADC values and higher FA values than canine meningiomas
Summary
Meningiomas are the most common intracranial tumor in dogs and cats. Comparison Canine and Feline Meningiomas is typically observed [6]. Due to some of these characteristic MRI findings, meningiomas can be presumptively diagnosed by conventional sequences, the definitive diagnosis is only made with histopathology. Surgical resection is often selected for canine and feline meningiomas [7, 8]. In feline meningiomas, surgical resection is associated with a significantly longer survival time after diagnosis than other treatment strategies [1, 2]. The consistency of meningiomas is an important factor in developing a strategy for surgical resection and predicting the degree of removal; a solid tumor is peeled off, whereas a fragile tumor may be removed by suctioning. Diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) have been used to predict the consistency of the tumors in human medicine [9, 10]
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