Abstract

Objective To investigate the healing effect of body anticoagulation and local thrombolysis therapy on patients with cerebral venous sinus thrombosis (CVST).Methods Forty two patients with CVST,admitted to our hospital from January 2008 to September 2011,were selected; these patients were divided into body anticoagulation group (n=21) and local thrombolysis group (n=21) according the treatment methods.The National Institutes of Health Stroke Scale (NIHSS) scores,modified Rankin Scale (mRS) scores,angiography imaging and adverse reactions after the treatments were compared between the two groups.Results The nervous system function defect improvement in the body anticoagulation group (33.4％) was significantly lower than that in the local thrombolysis group (61.9％,P＜0.05).The mRS scores in the local thrombolysis group was significantly lower than those in the body anticoagulation group (P＜0.05).Angiography after treatment showed that the completely recanalization rate in the local thrombolysis group was significantly higher than that in the body anticoagulation group (P＜0.05).Conclusion Local thrombolysis,enjoying better effect on nervous system function defect improvement than body anticoagulation,can help the nerve function recovery. Key words: Cerebral venous sinus; Body anticoagulation; Local thrombolysis

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