Abstract
AimThe aim of the present in vitro study is to evaluate and compare antimicrobial efficacy of commercially available child’s dental formulas in reduced concentrations containing different forms of fluoride against Streptococcus mutans activity.Materials and methodsThe selected dentifrices were prepared in dilutions of 1:1, 1:2, 1:4, 1:8, and 1:16 using sterile pyrogen-free distilled water. Various dilutions of the selected toothpaste slurries were incubated in the agar plate containing pure strains of S. mutans, and antimicrobial activity of each was assessed by measuring the diameter of zones of inhibition (in mm). Agar well plate diffusion method and minimum inhibitory concentration (MIC) determination were the methods used in this study. The inhibitory circle of each dentifrice was measured and MIC was achieved by considering the value of diameter of the circle.ResultsThe results of the study showed that even at a lower concentration of fluoride, inhibition halos were obtained for all the formulations at different dilutions.ConclusionThe kid’s formulations having lower fluoride concentration show antimicrobial activity even after dilutions. Thus, commercially, the fluoride concentrations can be further lowered down in the dentifrices, thereby reducing the risk associated with fluoride.How to cite this articleMalhotra R, Singla S, Shashikiran ND. Comparison ofAntimicrobial Activity of Child Formula Dentifrices at different Concentrations: An in vitro Study. Int J Clin Pediatr Dent 2017;10(2):131-135.
Highlights
The paradigm shift in the field of dentistry has led to the adoption of specific preventive treatment protocols or intervention, based on the current assessment of caries1-3Department of Pedodontics and Preventive Dentistry, People’s College of Dental Sciences & Research Centre, Bhopal, Madhya Pradesh, IndiaLevy[2] has stated that a dentifrice is the most common source of topical fluoride for young children
The fluoride concentrations can be further lowered down in the dentifrices, thereby reducing the risk associated with fluoride
The prepared dentifrice slurries were evaluated for antimicrobial activity against S. mutans
Summary
The paradigm shift in the field of dentistry has led to the adoption of specific preventive treatment protocols or intervention, based on the current assessment of caries1-3Department of Pedodontics and Preventive Dentistry, People’s College of Dental Sciences & Research Centre, Bhopal, Madhya Pradesh, IndiaLevy[2] has stated that a dentifrice is the most common source of topical fluoride for young children. The paradigm shift in the field of dentistry has led to the adoption of specific preventive treatment protocols or intervention, based on the current assessment of caries. 1-3Department of Pedodontics and Preventive Dentistry, People’s College of Dental Sciences & Research Centre, Bhopal, Madhya Pradesh, India. Levy[2] has stated that a dentifrice is the most common source of topical fluoride for young children. They are considered to ingest enough of fluoride from a dentifrice alone to be at risk of conditions like dental fluorosis.[3] Deliberate ingestion of toothpaste may occur because of an uncontrolled swallowing reflex of children aged less than 6 years. The antimicrobial efficacy of low-fluoride toothpastes still remains unclear
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