Comparison by real-time three-dimensional echocardiography of left ventricular geometry in hypertrophic cardiomyopathy versus secondary left ventricular hypertrophy

Abstract

Calculation of left ventricular (LV) volume by 2-dimensional echocardiography (2DE) has been suboptimal due to the complex LV cavity geometry. Three-dimensional echocardiography (3DE) provides improved accuracy for LV volume and function compared with current 2D algorithms. 1 Siu S.C Levine R.A Rivera J.M Xie S.W Lethor J.P Three-dimensional echocardiography improves noninvasive assessment of left ventricular volume and performance. Am Heart J. 1995; 130: 812-822 Abstract Full Text PDF PubMed Scopus (67) Google Scholar Three-dimensional echocardiography is more accurate than standard 2D methods for measuring LV mass 2 Sapin P.M Gopal A.S Clarke G.B Smith M.D King D.L Three-dimensional echocardiography compared to two-dimensional echocardiography for measurement of left ventricular mass anatomic validation in an open chest canine model. Am J Hypertens. 1996; 9: 467-474 Crossref PubMed Scopus (28) Google Scholar and is a promising technique for calculation of LV ejection fraction, with excellent correlation with radionuclide angiography. 3 Nosir Y.F Fioretti P.M Vletter W.B Boersma E Salustri A Postma J.T Rejis A.E Ten Cate F.J Roelandt J.R Accurate measurement of left ventricular ejection fraction by three-dimensional echocardiography. A comparison with radionuclide angiography. Circulation. 1996; 94: 460-466 Crossref PubMed Scopus (158) Google Scholar We used real-time 3DE to evaluate total and segmental LV volume, ejection fraction, and myocardial mass in hypertrophic cardiomyopathy (HC) and compared the finding with those in patients with LV hypertrophy from other causes.