Abstract
Comparison between Intra-Arterial Thrombolysis and Intravenous Thrombolysis in Ischemic Stroke Patients: A Meta-Analysis
Highlights
Acute cerebral infarction, commonly referred to as ischemic stroke, is a common disease of the nervous system
Searched databases and strategies PubMed, Embase, and Cochrane Central Register of Controlled Trials databases were searched for studies reporting the comparison of intra-arterial thrombolysis (IAT) and intravenous thrombolysis (IVT) for the treatment of patients with ischemic stroke from January 1, 2000, to March 16, 2019, were reviewed
Complete recanalization in IAT was better than that in IVT group (RR = 0.58, 95% confidence interval (CI) [0.48, 0.71], P < 0.00001; P for Heterogeneity = 0.70, I2 = 0%)
Summary
Commonly referred to as ischemic stroke, is a common disease of the nervous system It is associated with high disability and mortality rates, causing a serious adverse impact on human health and normal life [1,2,3]. Related studies showed that intravenous application of rt-PA within 4.5 hours after the onset of cerebral apoplexy quickly restored cerebral blood perfusion and effectively alleviated the symptoms of hypoxia in ischemic penumbra [7,8,9]. This in turn greatly reduced the mortality and disability rates in patients with stroke. To investigate the efficacy and safety between intra-arterial thrombolysis (IAT) and intravenous thrombolysis (IVT) in ischemic stroke patients
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