Abstract
Nano-silver particles are the integral aspect in functional nanotechnology filed. These nanoparticles have antibacterial and antifungal characteristics. Combination therapy is one of the new and specific methods for therapy of diseases in medicine and pharmacology fields. Interaction of alcoholic eucalyptus and nano-silver could be not performed in many investigations. For this reason, in this investigation, synergic effect of alcoholic eucalyptus and nano-silver in growth inhibition of Aspergilus niger were assayed A.niger were cultured in PDA medium. These fungi were treated with nanosilver and nano-silver -Eucalyptus ethanol extraction mixture in 12.5 and 50-ppm concentration. Then, Morphological changes and colony number in treatment and control groups were compared. Results of these investigations were shown that growth rate of A.niger decreased significantly (P<.01) 8 day after treatment. In addition, growth and colony number of A.niger decreased significantly (P<0.01) in 12.5ppm concentration of nano-silver -Eucalyptus 24 day after treatment. These found could be suggested the therapy of human fungal diseases in medicine will be performed with mixture of nano-silver and eucalyptus ethanol extract. This nanomaterial could be used as antifungal agents. Specific investigations are necessary to improved that this combination has not any side effect in human. This nanomaterial could be suggested as a minor antifungal drug.
Highlights
Introduction with medical applicationsEucalyptus leaves haveOne of greatest problems human faces today is how to eucalyptol (Paux et al, 2004), Terpene alcohols, aliphatic combat against the microorganisms, which have aldehydes, isoamyl alcohols and Some of such gradually become resistant to chemical medicines
Considering the removed the medicine, but this approach has its own borders between the various sciences at present, it is disadvantages, especially the enhanced risk from these undeniable and inevitable to use the nanotechnology in chemical elements, created side effects, and their medical sciences and pharmacology
The other disadvantage nanotechnology is nano-silver particles following carbon resulted from such medicines is that the increase in their nano tubes in terms of widespread applications, which side effects results in such diseases more severe and involve in many antimicrobial usages and in other dangerous than the initial ones
Summary
Introduction with medical applicationsEucalyptus leaves haveOne of greatest problems human faces today is how to eucalyptol (Paux et al, 2004), Terpene alcohols, aliphatic combat against the microorganisms, which have aldehydes, isoamyl alcohols and Some of such gradually become resistant to chemical medicines. The other disadvantage nanotechnology is nano-silver particles following carbon resulted from such medicines is that the increase in their nano tubes in terms of widespread applications, which side effects results in such diseases more severe and involve in many antimicrobial usages and in other dangerous than the initial ones. The present project compares the antibacterial effects of alcoholic extract of eucalyptus with the nano-silver particles on fungus - Aspergillus niger.
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