Abstract
The aim of current analysis was to compare the efficacy of intravenous ciprofloxacin and ceftazidime for treating spontaneous bacterial peritonitis (SBP) in patients with liver cirrhosis. A retrospective study was conducted in the Medicine Department of SIMS, Lahore, from September 2021-September 2022. The study selected 110 cirrhosis patients with SBP were included in the study and were divided into two groups, A and B. Group A (n=55) was administered ciprofloxacin intravenously, and group B (n=55) was administered ceftazidime intravenously. The patients diagnosed with type 1 hepatorenal syndrome were treated with albumin and terlipressin daily. The clinical signs and causes of infection did not vary between both groups. The infection was resolved in 50 patients (90.9%) ceftazidime patients and in 51 patients (93%) ciprofloxacin patients. Out of 17 patients who developed, 10 patients (58.8%) completely recovered after terlipressin and albumin treatment, 1 (5.8%) showed partial response, and 6 (35.3%) did not respond. Switch therapy with ciprofloxacin and ceftazidime is equally effective in treating spontaneous bacterial peritonitis in cirrhotic patients with ascites.
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