Abstract
DNA computing is a hot research topic in recent years, molecular logic gate is an important foundation of DNA computer architecture and implementation. Local hairpin DNA chain substitution reaction can increase the reliability of molecular logic gates, Make the reaction more efficient and more thoroughly. In this paper, using local hairpin DNA strand displacement, the comparator circuit is coded and simulated base on the double logic circuit. The simulation results further confirmed the feasibility and effectiveness of the DNA strand displacement reaction in the study of biochemical logic circuits, The comparator circuit can be used for biological computer and building large-scale molecular logic circuits in the future.
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