Comparative study on test results of colposcopy and liquid based thinprep cytology in screening of cervical lesions

Abstract

Objective To compare and study the value of colposcopy and liquid based thinprep cytology test (TCT) in screening of cervical lesions.Methods 1792 cases of married women were selected and detected by adopting new cypress automatic ultrathin liquid based TCT and colposcopy for screening cervical lesions.Pathology results being served as a reference,the sensitivity,specificity and accuracy of two methods were comparatively analyzed.Results The negative rate of ultrathin liquid base cytology was 85.2％ and the positive rate was 14.8％.The negative rate of colposcopy was 90.1％ and the positive rate was 9.9％.The positive rate of colposcopy was higher than that of the ultrathin liquid based cytology (P ＜ 0.05).The sensitivity,specificity and accuracy of the ultrathin liquid based cytology were 86.1％,91.8％ and 91.3％ respectively,while the sensitivity,specificity and accuracy of colposcopy were 93.4％,97.8％ and 97.5％ respectively.The sensitivity,specificity and accuracy of the ultrathin liquid based cytology were compared with those of the ultrathin liquid based cytology with a reference of pathology results.There were statistical significant differences between two methods (P ＜ 0.05).Conclusion The results of colposcopy are more relatively reliable than those of liquid based TCT in screening cervical lesions. Key words: Liquid based thinprep cytology test; Colposcopy; Cervical lesions; Screening; Comparative study