Abstract
Aim : To as sess the quality of 10 brands of Amoxicillin Trihydrate 500 mg capsules. Study Design: Experimental . Place and Duration of Study: Experimental drugs were purchased from pharmacy in Okada and Benin and experimental work was carried out in Pharmaceutical Te chnology laboratory, Igbinedion University Okada Methodology: A specific quality control method was developed for the determination and comparative study of the capsules and the quality was assessed through evaluation of organoleptic properties, uniformity of weight, disintegration, dissolution using the spectrophotometric method, moisture uptake as well as comparing analytical method (titration) and HPLC method for the determination of content uniformity. All the brands have suitable appearance. Results: 7 brands passed the weight variation test, 9 brands passed the content uniformity test with
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