Abstract
The current study aimed to know the protective effect of the aqueous extract of Cinnamon zeylanicum and the free Cinnamon nanocomplex loaded with MTX treatment to reduce the effect of arthritis induced with Complete Freunds (CFA Adjuvant) in male albino rats by studying some changes in immunological and histological parameters. Atomic force microscope (AFM) revealed the appearance of changes in the surface of nanocomposites loaded with treatment. The immunological results indicated that the induction of rheumatoid arthritis (RF) in male white G2 rats led to a significant increase (P<0.05) in the level of IL-8 cytokine concentrations 86.31 pg/ml compared with the negative control group at 24.41 pg/ml. There was also a significant decrease (P<0.05) in the level of IL-8 concentration in the G7 group dosed with cinnamon nanocomplex loaded with MTX treatment pg/ml (37.45) and the results of histological parameters showed that there was a significant increase in white blood cells in the positive control group G2 (14.00) compared to With the negative control group G1 (5.433), while in the group G7 there was a significant decrease (p<0.05) (9.433).
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
