Comparative study of malaria course

Abstract

Globally in 2022, there were an estimated 249 million malaria cases and 608 000 malaria deaths in 85 countries. Malaria is a major cause of death in tropical and sub-tropical countries, killing each year over 1 million people globally. Although effective ways to manage malaria now exist, the number of malaria cases is still increasing, due to several factors. In this emergency situation, prompt and effective diagnostic methods are essential for the management and control of malaria. The most common early symptoms of malaria are fever, headache and chills. Symptoms usually start within 10– 15 days of getting bitten by an infected mosquito. Symptoms may be mild for some people, especially for those who have had a malaria infection before. Because some malaria symptoms are not specific, getting tested early is important. For primary malaria vivax the symptoms such as non-typical fever, nausea, vomiting, myalgia, absence of tachycardia, severe anemia, normocytosis in blood are characteristic for a significant part of cases, while the neurological disturbance is observed during the severe course. At the same time, heart, liver, and kidney complications are observed during the mild course that is necessary to consider during the diagnosis and disease treatment. Keywords: Malaria vivax, prodromal period, fever, alanine aminotransferase, aspartate aminotransferase