Abstract
Objectives: To Compare low molecular weight heparin and conventional heparin in acute myocardial infarction and unstable angina. Materials and Methods: 100 patients with symptoms of acute MI and unstable angina were included in the study.50 patients were treated with Conventional Heparin and 50 treated with low molecular weight heparin for 5 days . Patients were monitored by serial ECGs, echocardiograms, blood counts, bleeding time and clotting time and were followed every week for 6 weeks. Results: Relief of chest pain was seen in 52% of patients on conventional heparin and in 66% on low molecular heparin on the 2 nd day. Bleeding complications (haematemesis in 4% and haemoptysis 2%) occurred in patients on standard heparin while no such effects were seen in patients on low molecular heparin. Conclusion: Low molecular weight heparin is equally effective in the treatment of acute myocardial infarction and unstable angina as that of conventional heparin with the added advantage of low complication rate and ease of administration.
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