Abstract
Background:- Iron deficiency is the principle cause for nutritional anemia. The aim of the study was to compare the efficacy of oral iron therapy with intravenous iron therapy in the treatment of iron deficiency anemia during postpartum period Material and Methods:- A clinical observational studY. Results :- .On day 5 of the  intravenous iron group , there was statistically significant increase in serum ferritin level from 11.47 + 1.655 µg/l to 41.44 + 6.500 µg/l (p value <0.01), and the ferritin level remained elevated on day 14 and day 40. There was significant increase in mean  Hb level from 7.76 + 0.7137 g/dl  to 10.78 + 0.7679 g/dl on day 40 (p value < 0.01) in oral iron group. There was increase in mean Hb level from7.47 + 0.7678 g/dl  to 11.41 + 0.7908 g/dl on day 40 in injectable iron group ,which was  statistically significant. (p value < 0.01) Intravenous iron sucrose did not result in any serious adverse reactions. Conclusion:- Intravenous iron sucrose administration increases the hemoglobin level and serum ferritin levels more rapidly ,without any serious adverse effect in comparison with oral ferrous sulphate in women with iron deficiency anemia in the postnatal period .
Highlights
Anemia is one of major contributing factor in maternal mortality and morbidity in third world countries and according to the WHO, contributes to 20% maternal deaths
Postpartum anemia is associated with longer hospital stays, depression, anxiety, and delayed infant development.4At the present time, there is no consensus on the management of postpartum anemia, and clinical practice varies from one clinic to another
Specific objectives of the study were 1)To compare the efficacy of treatment with oral ferrous sulphate or intravenous ferrous sucrose on iron deficiency anemia during postpartum period. 2)To note the untoward reactions and complications of intravenous iron sucrose therapy
Summary
Anemia is one of major contributing factor in maternal mortality and morbidity in third world countries and according to the WHO, contributes to 20% maternal deaths. In practice the use of iron dextran is not generally recommended due to the unpredictable risk of life-threatening or serious acute reactions in 0.6 to 2.3% of patients and the availability of safer alternative drugs.[7,8,9] Parental iron administration with ferrous sucrose is available and can be used for treatment of iron deficiency anemia in postpartum period.[10] Present study was a prospective randomized comparison between intravenous iron sucrose and oral iron in treatment of postpartum anemia. Specific objectives of the study were 1)To compare the efficacy of treatment with oral ferrous sulphate or intravenous ferrous sucrose on iron deficiency anemia during postpartum period. Specific objectives of the study were 1)To compare the efficacy of treatment with oral ferrous sulphate or intravenous ferrous sucrose on iron deficiency anemia during postpartum period. 2)To note the untoward reactions and complications of intravenous iron sucrose therapy
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