Comparative Study of Imaginary Compounds against Plasmodium Falciparum

Abstract

In the pursuit of developing innovative antimalarial medications, particularly targeting the pernicious Plasmodium falciparum, computational methods have assumed an increasingly crucial role. analysis of three primary computational techniques: Ligand-based Virtual Screening (LBVS), Molecular Docking, and Quantitative Structure-Activity Relationships (QSAR) in the realm of antimalarial drug discovery. The initial technique, LBVS, has swiftly become an invaluable asset for identifying novel drugs. Molecular docking proves invaluable in virtually screening extensive compound libraries, identifying potential inhibitors against these targets The significance and potential of computational methods in the realm of antimalarial drug discovery, presenting a trio of techniques as potenttools against the formidable adversary, Plasmodium falciparum Keywords: virtual screening, Plasmodium Falciparum, Molecular docking ,QSAR.