Abstract
The aim of this research work was to carry out a comparative study on the aqueous extracts of the leaves and fruits of Garden egg (Solanum melongena) using alloxan induced diabetic guinea pigs. Blood glucose level analysis was used as diabetic indices. Z-test was used in comparing the mean fasting blood glucose level of alloxan induced diabetic guinea pigs after administration of aqueous leaf extracts and that of the aqueous extracts of the fruits of Garden egg (Solanum melongena) against the negative control (0.9%N/S) and positive control group (Glibenclamide solution).The results showed that there was a significant difference between the group that had oral administration of aqueous leaf extracts and the negative control group (p 0.05).
Highlights
There is two major tropical botanical flowering or dietary plants species in this family of solanaceae
Antidiabetic efficacy of Solanum melongena was established by different researchers [1].Solanum Melongena may be used by patient suffering from raised intraocular pressure and convergence insufficiency[2]
It is known that diabetes mellitus is one of the commonest tropical endocrine or metabolic diseases [4]
Summary
There is two major tropical botanical flowering or dietary plants species in this family of solanaceae. In this study, Solanum melongena species was used. Solanum species are popularly known as Garden egg plants. These plants are made up of leaves, fruits, stems and roots. In herbal practice, these aqueous leaf extracts are extensively used in management of diabetes mellitus (Arazu and Okafor 2005). Other health benefits of Solanum melongena are cardio. Notwithstanding, the present study was undertaken in an effort to further search for a better curative and safe agents for treatment and management of diabetes mellitus
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