Abstract

Comparative study of Four Layer Compression Bandaging and Topical Human Epidermal Growth Factor in Chronic Venous Leg Ulcer

Highlights

  • Leg ulcers are defined to be loss of epidermal and dermal tissues of leg or foot

  • The Human epidermal growth factor (H-EGF) dressing group was very effective as there was faster ulcer healing when compared to regular four layered dressing

  • Topical H-EGF along with four layer dressing can be used in chronic venous leg ulcer, as it significantly hastens healing time than the conventional four layer bandaging technique alone

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Summary

Introduction

Leg ulcers are most commonly caused due to venous Insufficiency, arterial insufficiency, neuropathy often due to diabetes and ulcer from prolonged pressure and ischemia [1]. The goals of non-operative treatment: for venous ulceration are to promote healing of the existing ulcer and prevent recurrences while allowing the patient to maintain a normal ambulatory status. Compression therapy remains the primary non-operative treatment for chronic venous insufficiency despite progress in both ablative and reconstructive venous surgery [4]. 1% of the population suffer from a leg ulcer at some stage during their lives. Venous leg ulcers are consequence of chronic venous insufficiency

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