Abstract
BackgroundManagement of patients with sinonasal polyps ranges from systemic steroid to functional endoscopic sinus surgery; however, many patients refuse surgery or are contraindicated to receive systemic steroid. Intrapolyp steroid injection has been recently used to apply a higher concentration of steroids into the nasal polyps and on the other hand protecting the patient from the side effects of systemic steroid. In this study, we have tested intrapolyp steroid injection on 22 patients (injection group) and the results were statistically compared with the results of 16 patients treated by oral steroid (oral group) subjectively by total nasal symptoms score and objectively by total nasal polyp score and on CT films by using Lund Mackay scoring system, patients of both groups have been followed up for 3 months.ResultsAfter treatment, there was a statistically significant decrease in the score in both groups, with no significant difference in between them. No serious complications as visual disturbance apart from mild self-limited bleeding detected in only 2 injections (3%) of all 66 injections.ConclusionIntrapolyp steroid injection is an effective, easy, and safe procedure with short-lasting effect for at least 3 months. It was proven to show comparable results to oral steroids as both modalities showed a statistically significant improvement subjectively and objectively. However, cases with extensive bulky polyposis were resistant to complete eradication by injection and they may need surgical intervention.
Highlights
Management of patients with sinonasal polyps ranges from systemic steroid to functional endoscopic sinus surgery; many patients refuse surgery or are contraindicated to receive systemic steroid
Using systemic steroid in the treatment of sinonasal polyposis carries the risk of systemic side effects [3]
This study aimed to study and evaluate the efficacy and safety of intrapolyp steroid injection in the treatment of sinonasal polyposis, comparing these results with that of oral steroid
Summary
Management of patients with sinonasal polyps ranges from systemic steroid to functional endoscopic sinus surgery; many patients refuse surgery or are contraindicated to receive systemic steroid. Intrapolyp steroid injection has been recently used to apply a higher concentration of steroids into the nasal polyps and on the other hand protecting the patient from the side effects of systemic steroid. Management of sinonasal polyposis clues range from topical and systemic steroids to functional endoscopic sinus surgery [1]. Even it has a wide range of usage but sometimes do not succeed to provide cure and can be associated with a nasal septal perforation [2]. Using systemic steroid in the treatment of sinonasal polyposis carries the risk of systemic side effects [3]. Intrapolyp steroid injections have been recently used to apply a higher
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