Abstract
Pet ether, ethyl acetate and ethanolic extracts of Mangifera indica L. Var. Thotapuri and Mangifera indica L. Var. Neelam were taken for anthelmintic activity against Indian earthworm Pheritima posthuma . Various concentrations of both extracts were tested and results were expressed in terms of time for evoked response, paralysis and time for death of worms. Piperazine citrate was used as a reference standard and distilled water as a control group. Dose dependent activity was observed in both plant extracts but Mangifera indica L. Var. Thotapuri shows more activity as compared to Mangifera indica L. Var. Neelam .
Highlights
Since the time immemorial, our traditional system of medicine and folklore claiming that medicinal plants as a whole or their parts are being used in all types of diseases successfully including antibacterial and anthelmintic, anti-inflammatory etc[1]
Worms were observed at regular intervals for evoked response, paralysis and death and the time of paralysis and death in each concentration was recorded in the table 3
Preliminary phytochemical screening has shown the presences of alkaloids were present in ethanol extract of Thotapuri and pet ether and ethanol extracts of Neelam
Summary
Our traditional system of medicine and folklore claiming that medicinal plants as a whole or their parts are being used in all types of diseases successfully including antibacterial and anthelmintic, anti-inflammatory etc[1]. Plant derived drug serve as a prototype to develop more effective and less toxic medicines[2,3]. The gastro-intestinal helminthes becomes resistant to currently available anthelmintic drugs there is a foremost problem in treatment of helminthes diseases[6]. The Mangifera indica (mango) is one of the choicest fruit crops of tropical and subtropical regions of the world, especially in Asia. The characteristic of Mangifera indica is the trees are deep rooted, symmetrical evergreens that the height is about 90 feet and widths of 80 feet.[7,8,9] The mango has a long taproot that often branches just below ground level, forming between two and four major anchoring taproots that can reach 6 m (20 ft) down to the water table. Distribution of the finer roots changes seasonally with the moisture distribution in the soil.[10,11]
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