Abstract
Sneha Kalpana is one of the important and highly established kalpanas of Ayurveda. It is the method of preparing a medicine in which the lipid soluble and aqueous soluble active principles of the Aushadhis are incorporated in to Sneha Dravya. Prior to snehapaka vidhi, Sneha is subjected to Murchana process, aiming to eliminate Ama dosha and enhance potency. Addressing the global burden of Apasmara (epilepsy) and the growing acceptance of Ayurveda, cost-effective medicines are crucial. Despite existing studies, ancient texts hold untapped potential, with secondary preparations like Sneha Kalpana offer extended shelf life compared to Panchavidha Kashaya Kalpana. Kushmanda Ghrita is a unique sneha kalpana mentioned in the text of Chakradatta, which is indicated for the management of Apasmara. The ingredients are Kushmanda Swarasa, Yastimadhu and Go-Ghrita. Total six samples were prepared in three batches, three samples prepared by Murchita Ghrita and other three samples with Amurchita Ghrita. All the Ghrita samples were subjected to analysis for physico-chemical parameters, to develop the SOP and to validate Murchana process.
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