Comparative functional neuroanatomy between implicit and explicit memory tasks under negative emotional condition in schizophrenia

Abstract

PurposeTo evaluate the brain activation patterns in response to negative emotion during implicit and explicit memory in patients with schizophrenia. Material and methodsFourteen patients with schizophrenia and 14 healthy controls were included in this study. The 3.0T fMRI was obtained while the subjects performed the implicit and explicit retrievals with unpleasant words. ResultsThe different predominant brain activation areas were observed during the implicit retrieval and explicit with unpleasant words. ConclusionThe differential neural mechanisms between implicit and explicit memory tasks associated with negative emotional processing in schizophrenia.