Abstract
The in vitro antioxidant potential assay between ethanolic extracts of two species from the genus Vitex (Vitex negundo L. and Vitex trifolia L.) belonging to the Lamiaceae family were evaluated. The antioxidant properties of different extracts prepared from both plant species were evaluated by different methods. DPPH scavenging, nitric oxide scavenging, and β-carotene-linoleic acid and ferrous ion chelation methods were applied. The antioxidant activities of these two species were compared to standard antioxidants such as butylated hydroxytoluene (BHT), ascorbic acid, and Ethylene diamine tetra acetic acid (EDTA). Both species of Vitex showed significant antioxidant activity in all of the tested methods. As compared to V. trifolia L. (60.87–89.99%; 40.0–226.7 μg/mL), V. negundo has been found to hold higher antioxidant activity (62.6–94.22%; IC50 = 23.5–208.3 μg/mL) in all assays. In accordance with antioxidant activity, total polyphenol contents in V. negundo possessed greater phenolic (89.71 mg GAE/g dry weight of extract) and flavonoid content (63.11 mg QE/g dry weight of extract) as compared to that of V. trifolia (77.20 mg GAE/g and 57.41 mg QE/g dry weight of extract respectively). Our study revealed the significant correlation between the antioxidant activity and total phenolic and flavonoid contents of both plant species.
Highlights
The genus Vitex (Lamiaceae) contains 270 species with diverse medicinal active constituents and properties
Ethanol was proven to be excellent for the extraction of phytochemicals as evident from the results (Table 1)
Alkaloids were not detected in the petroleum ether extract of V. negundo
Summary
The genus Vitex (Lamiaceae) contains 270 species with diverse medicinal active constituents and properties. These species are predominantly trees and shrubs, found in tropical and subtropical regions. Some of Vitex species, including Vitex negundo, Vitex glabrata, Vitex leucoxylon, Vitex penduncularis, Vitex pinnata, and Vitex trifolia, are found in India [1]. These species are commonly used in traditional medicine to treat a wide range of ailments, such as depression, venereal diseases, asthma, allergy, skin diseases, snakebite, and body pains [2,3]. Many plants of the genus Vitex are used for their interesting biological activities, such as treatment of cough, wound healing, larvicidal, anti-HIV, anticancer, and trypanocidal [4,5,6]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
