Abstract
Tablet is unit solid dosage form containing drug substance with diluents and prepared by either compression or molding method. A recent development in technology has presented variable dosage alternatives for patients. The experimental design has conducted comparative evaluation of different types of marketed Diclofenac Sodium Tablets in which Sustained release (100mg),enteric coating(50mg), dispersible tablet(50mg) was taken. Dissolution pattern of marketed Diclofenac sodium sustained release, enteric coated and dispersible tablets and interpret the results obtained. Also thickness, weight variation and disintegration time, hardness (kg/cm 2) , friability, assay, size & shape, absorption. %drug release the data was used to do the evaluation studies. All the three tablets compared with official standard were found within the range. Dissolution studies showed that Diclofenac sodium was slowly released in sustained release tablet compared to that of enteric coated tablet and drug release from dispersible tablet was very fast.
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