Abstract
Candida albicans and Enterococcus faecalis are the most resistant and predominant microorganisms recovered from root canals of teeth where, previous treatment has failed. Thorough debridement of an infected root canal and complete elimination of microorganisms are objectives of an effective endodontic therapy. Over the past decade, interest in drugs derived from medicinal plants has markedly increased. In dentistry,phytomedicines has been used as an anti-inflammatory, antibiotic, analgesic, sedative and also as endodontic irrigant. Many plants with biological and antimicrobiological properties have been studied since there has been a relevant increase in the incidence of antibiotic overuse and misuse. In endodontics, because of the cytotoxic reactions of most of the commercial intracanal medicaments used and their inability to eliminate bacteria completely from dentinal tubules, trend of recent medicine use intends to use biologic medication extracted from natural plants. The aim of the study was to explore the antimicrobial efficacy of newer irriganting agents which would probably be as effective or more and at the same time less irritating to the tissues than sodium hypochlorite. The objective of this ex-vivo study was to compare the antimicrobial activity of 2% sodium hypochlorite, propolis, neem leaf extract, turmeric and liquorice against E. Faecalis and C. Albicans, using the agar diffusion method. Results: Neem leaf extract showed the highest zone of inhibition against E.faecalis and C.Albicans.
Published Version
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