Abstract
The anthelmintic activities of aqueous, methanolic and acetone extract of Acalypha indica L. and Euphorbia hirta L. belong to the family Euphorbiaceae were evaluated separately on Indian adult earthworm Pheretima posthuma (Annelida). Extracts were prepared using soxhlet extraction and crude extract preparation methods with various concentrations (10, 25 and 50 mg/ml). Each extracts were tested in the bioassay, which involved determination of time of paralysis and time of the death of the worms. All extract were able to show anthelmintic activity at all concentration. The activities are well comparable with standard drug albendazole and piperazine citrate as positive control, distilled water (for aqueous extract) was used as negative control did not show any anthelmintic activity. The methanolic extract of both plant exhibited dose dependent anthelmintic activity showing maximum efficacy at 50 mg/ml concentrations. Methanolic and acetone extracts exhibit significant anthelmintic activity in present study. Methanolic extract of Acalypha indica L. have profound anthelmintic activity
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