Comparative Efficacy of Whole-Brain Radiotherapy Combined with Supplemental Precision Radiotherapy and Whole-Brain Radiotherapy Alone for Brain Metastases

Abstract

Objective: To investigate the efficacy of whole-brain radiotherapy combined with supplemental precision radiotherapy compared to whole-brain radiotherapy alone for brain metastasis. Methods: Twenty-six cases of patients with brain metastasis were observed from January 2020 to June 2023. Thirteen cases each were randomly assigned to the observation group and the control group. The patients in the observation group received whole-brain radiotherapy combined with supplemental precision radiotherapy, while those in the control group received only whole-brain radiotherapy. Results: Comparing the quality of life scores between the two groups, the data from the observation group was significantly superior (P < 0.05). The survival rate of the observation group was higher than that of the control group, and their survival time was longer (P < 0.05). Additionally, compared with the control group, the observation group exhibited lower levels of various serum tumor factors after treatment (P < 0.05). Conclusion: Whole-brain radiotherapy combined with supplemental precision radiotherapy demonstrates improved clinical efficacy, prolonged survival time, and enhanced quality of life for patients with brain metastasis. These findings warrant further study and promotion.