Abstract
Microbial infections are the most complicated challenges of modern-day medical practices. Such infections become fatal when acquired from hospitals or other health care facilities. To tackle the challenges of hospital-acquired infections (HAIs), different classes of chemical disinfectants are used. Out of these chemical disinfectants, Quaternary Ammonium Compounds (QACs) based disinfectants are widely used because of their advantageous properties. Large-scale use of QACs led to reporting of resistance. To further enhance the efficacy and reduce toxicity, manufacturers of QACs developed newer compounds. However, disinfectants in hospitals are solely used in good faith and hospitals don't have an adequate policy to see the efficacy using standardized methods. Efficacy testing of QACs disinfectant is very important to reduce HAIs. Hence, bactericidal activities of different generation QACs disinfectants were evaluated as per the standardized method EN 1040. All QACs disinfectants demonstrated more than 5 log reductions and complied with the requirement of EN 1040.
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